BIF101 Midterm MCQs

BIF 101 Midterm M.C.Q

Lecture 1 to 50

1. Which is of the following is the basic unit life? Cell
2. ___________ is the tendency of an atom to attract electrons towards itself. Electronegativity
3. How many______ % of human body consist of water? 70 %
4. Which kind of reaction is Monomers join H2O Removal? Condensation
5. ____ refers to the biology of the molecules related to genes, gene products and heredity. Molecular Biology
6. Who synthesis urea in 1828? Friedrich Wohler
7. The first enzyme__________ was discovered by Anselme Payen in 1833. Diastase
8. DNA was discovered by__________. Friedrich Miescher
9. James Watson and Francis Crick discovered the double helical structure of DNA in __________. 1953
10. Marshall Nirenberg and Gobind Khorana found that 3 bases constitute a code word, called a___. Codon
11. The Human Genome Project (HGP) was launched in 1990 and completed in 2003.
12. How many components are present in a nucleotide? Three
13. The successive nucleotides of DNA are joined together through__________. Phosphodiester linkages
14. _________ deals with movement of genes and genetic traits from parents to offspring. TRANSMISSION

OR CLASSICAL GENETICS

15. _________ is the field in which computational and statistical techniques are applied to derive biological information from genome sequences. Genome informatics

Q16. Which one of the following is or is not a model organism?

17. _____ are the organisms whose Genetic material (DNA) is not enclosed in a nuclear membrane. Prokaryotes
18. Which one of the following is evolved from a bacterial endosymbiont? Mitochondria
19. Which one is First prokaryotic Genome was sequenced? Hemophilus influenza
20. The genome size of E. coil in_________ mbp. 4.6
21. Alkaptonuria is most common in children whose parents were first cousins_________. 12.5%
22. RNA molecule forms complimentary copy of one DNA strand, moves to cytoplasm serves as template for protein synthesis.
23. Human consist of how many genes? 25000
24. Genetic information flows from DNA to RNA to protein during cell growth.
25. flow of information from RNA “backwards” to DNA is possible in certain special circumstances due to the operation of_____________. Reverse transcriptase
26. The correct sequence of central dogma. DNA - RNA - Protein
27. Which on of the following is a stop codon? UAA, UAG, UGA
28. tRNA has 75-80 nucleotides with internal H- bonding.
29. In DNA the Adenine always pair with____________. Thymine
30. Which one of the following is not present in DNA? Uracil
31. _____ is the type of RNA that carries genetic information from DNA to the protein biosynthetic machinery of the ribosome. mRNA
32. The process of forming mRNA on a DNA template is known as_____________. Transcription
33. Which type of RNA serve as adapter molecules in the process of protein synthesis. tRNA
34. rRNA is a predominant material in the ribosomes constituting about 60% of its weight.
35. The protein-coding region(s) of each mRNA is composed of a contiguous, nonoverlapping string of codons

called _______________. Open reading frame (ORF)

36. mRNAs containing multiple ORFs are known as______. Polycistronic RNAs
37. A ribosome that has just completed translating the upstream ORF is positioned to begin translating from the start codon for the downstream ORF. Translational coupling
38. The heart of protein synthesis is the “translation” of nucleotide sequence information.
39. tRNA molecules are between 75 and 95 ribonucleotides in length.
40. Pseudouridine is derived from uridine by an isomerization in which the site of attachment of the uracil base to the ribose is switched from the nitrogen at ring position 1 to the carbon at ring position 5.
41. The large subunit contains the peptidyl transferase center, which is responsible for the formation of peptide bonds.
42. The A-site is the binding site for the aminoacylated-tRNA.
43. P-site is the binding site for the peptidyl-tRNA.
44. The E-site is the binding site for the tRNA that is released after the growing polypeptide chain has been transferred to the aminoacyl-tRNA.
45. The ribosome catalyzes a single chemical reaction — the formation of a peptide bond.