BIF401 Final Term Past Paper

BIF401 Final Term Past Paper

BIF 401 ( 5PM)

Bioinfirmatics paper Total qstn 47, mcqs are 32 Paper was easy Q:need of chous fasmen method Q: alphex helix regions in chou fasmen meethod Q:formula to calculate tetra peptide Q: why less energy used in folded rna as compare to unfloded Q: role of mass spectrometry in protein Q: domain in protein

*What happen in Jackson traceback algorithm if two or more scoring matrices scores higher construction ya range tha i think 3

Q1. Hydrophobic amino acids?

Q2. optimal energy function in protein?

Q3. PH<PK?

Q4. Need for chou fasman algorithm?

Q5. Blast and Fasta tools in sequence alignmnedt and its differences?

Q6. Protein scoring?

Q7. Why is it difficult to predict the structure of protein?

Q8. Describe the following?

1. role of amino acids.
2. folded protein.
3. denature protein

Q9. experimental techniques in bioinformatics?

Q10. Silico fragments comparison?

Q11. Describe PDB in the following.

1. TITLE;
2. SOURCE;

choufasman algorithem.??

improvements of choufasman algorthem?

limitaions of choufasman?

initio modeling??

scoring formulas??

ph>pk??

beta sheet by choufasman??

alpha helix by choufasman??

BIF 401 ( 5PM)

.yesterday BIF 401 on 2;30 pm PAPER WAS ...

pH value less than pk .2 Chao fasman ..5 Ab anitio devileers ..2. Sillico alogrithm ..5 Two groups of amino acids .2

Qno.1 what is principle of dynamic programming. 2 Qno.2 what is role of scoring scheme in top down proteomics.2 Qno.3 what happend when pH is less then pk value.2 Qno.4 what are the basic need in Chou Fasman Algorithim.2 Qno.5 what is ab initio modelling?describe its limitations.2 Qno.6 describe folliwing elements ,title,source,RAVDAT,COMPND.2 Qno.7 enlist famoys protein sequence database.2 Qno.8 write down characteristics of amino acids.3 Qno.9 why is structure prediction of protein is carried out.3 Qno.10 how many types of force involved in folding.3 Qno.11 why may we need to model protein structure when we have X rays and NMR twchnuques.3 Qno.12 why do hairpin loops reverse the chemical direction of molecules.3 Qno.13 how protein sequence are identified.5 Qno.14 what are the optimal energy function in protein structure predition.5 Qno.15 describe the following.5 a.advantage of folded protein over denature protein b.factors affect in folding protein c.role of amino acid d.goal of folding protein

Folded of protein goal Chou fasman Why difficult to determine structure of protien What is hydrophobicity of amino acids

Q1. Hydrophobic amino acids?

Q2. optimal energy function in protein?

Q3. PH<PK?

Q4. Need for chou fasman algorithm?

Q5. Blast and Fasta tools in sequence alignments and its differences?

Q6. Protein scoring?

Q7. Why is it difficult to predict the structure of a protein?

Q8. Describe the following?

1. role of amino acids.
2. folded protein.
3. denature protein

Q9. experimental techniques in bioinformatics?

Q10. Silico fragments comparison?

Q11. Describe PDB in the following.

1. TITLE;
2. SOURCE;

M.C.Q.S are so difficult related to the topics of chou fasman algorithum, fasta, protein amino acids, most were from final term syllabus

BIF 401 final paper today at 11:00 am

1. the term ExPANSy stands for?(2)
2. differntiate between bottom up proteiomiics and bottom down proteiomics (3)