BT605 Final Term Current Solved Objective and Subjective 2018

BT: 605

Subjective:

Q1. define biosafety?

•  prevention of large-scale loss of biological integrity,
•  prevention mechanisms,
•  conduction of regular reviews

Q2. facilities of bsl 3 lab?

Answer: Applicable to diagnostic / clinical/ research/ production/teaching facilities

•  potentially lethal disease through the inhalation route
•  all procedures must be performed in a biosafety cabinet

Q3. Define biosafety level ? (2 marks)

Answer: Definition: level of containment precautions

• isolate dangerous biological agents
• enclosed laboratory facility
• containment level (BSL-1 to BSL-4

Q4. Describe elements of surveillance? (2 marks)

• lighting
• alarms
• cameras

5. which additional facilities in BSL4 as compared to BSL3. (2)

6. Define biosecurity (3)

Answer: A set of preventive measures designed to reduce the risk of transmission of infectious agents.

It can be

• increases the level of assurance
• honesty, trustworthy, loyalty with government resources
• reduces the risk of loss and damage

7. Functions of technical advisory committee (5) · 8. Name protective equipment in first Aid. (5) · Protective equipment in first Aid:

• mouth piece for mouth-to-mouth resuscitation
• gloves-protections
• clean up kit for blood spills

9. How risk can be reduced through risk management describe the logical process (5)

10. What are bioweapons.what are their biological threats and also explain the efforts of mitigate them (10)

Answer: Bioweapons: It is defined as any infectious agent used intentionally to cause harm to others. Planning of an effective biowar defence-difficult task

Types:

1. Chemical weapons,
2. Radiological weapons,
3. Nuclear weapons

Defence against bioweapons:

• international cooperation
• transfer of technology
• support national actions

Biological threats:

• terrorist, non-state actors
• misuse of technologies
• theft from lab
• religious extremists
• locally hired agents
• frustrated cult

Efforts to mitigate:

• BTWC Act
• designation of focal point
• central implementation authori
• biosafety/biosecurity
• code of conduct /awareness

11. Duties of biosafety committe 3

Answer

• biosafety policies and code of practice
• review research protocols
• risk assessment formulation
• advice - sensitive discussion

12. What are potential threats of bioweapons 3

Answer: Potential threats:

• naturally present in the environment
• no major infrastructure
• no man power
• easier and faster
• cover large area
• difficult to diagnose and treat
• high mortality and mobility
• create panic

13. Risks of ionizing radiation 5 · Ionizing radiation · Risk:

• somatic effects: radiation induced cancers
• hereditary effects of radiation exposure to the gonads

Protection:

• minimize the time of exposure to radiation
• maximize the distance from the radiation source
• shielding the radiation source
• substituting with non-radiometric methods

Rules:

• radiation area
• work-bench area
• radioactive waste area
• emergency response

Q14. Measures require for TB lab? (3 marks)

•  codes of practice,
•  equipment
•  lab design and facilities,
•  health surveillance,
•  training,
•  waste handling

Concepts: waste handling, incineration, autoclaving,disinfection equipment, work areas, equipment

15. Activities of biosafety officers.