BIF101 Important Questions MCQs Long

PREPARED AND COMPOSED BY ZAINAB ARSHAD · BIF 101 ALL IMPORTANT QUESTIONS FOR FINAL TERM · FROM TOPICS 99 TO 150

SQ: What is National Human Genome Research Initiative (NHGRI)?

Answer: National Human Genome Research Initiative (NHGRI) a federally funded organization (NIH) started in 1988 (Francis

Collin)

• Celera, a commercial vendor (Craig Venter) joined the venture in 1998. Both

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simultaneously announced the completion of the project in 2000. Total 3.4 billion bases sequenced at a cost of $1/base

SQ: Define: Gene Expression Omnibus (GEO)

A public repository for the archiving and distribution of gene expression data submitted by the scientific community

Sq: what are the uses and benefits of Gene Expression Omnibus (GEO)?

Convenient for deposition of gene expression data, as required by funding agencies and journals Curated resource for gene expression data Browsing, querying, analysis and retrieval

SQ: MCQs: How many records of GEO ?

1)

Sample (GSM) preparation and description of the samples

Platform (GPL)

technology used and the features detected microarray or RNASeq

2)

Series (GSE)

defines a set of samples and how they are related

3)

Datasets (GDS)

sample data collections assembled by GEO

SQ: Define health informatics?

• It deals with the resources, devices, and methods required to optimize the acquisition, storage, retrieval, and use of information in health and biomedicine.

Q:What is MEDLINE?

• MEDLINE is the primary resource for biomedical journal articles