BT302 Midterm Current Papers Spring 2024 by Muhammad Zaman

•  Humans can make 10^7-10^8 different Ab molecules.
•  Recombination involves rearrangement of DNA in somatic cells… Somatic recombination.
•  Lymphoid linkage progenitor cells give rise to ------- B- lymphocytes, T- Lymphocytes, natural Killer, All of the given.
•  Major class of antibody produced during primary antibody response is - ------ lgM
•  During complement fixation test, lysis of RBCs indicates a ----- Complement fixation test. Negative
•  Which of the following comes under mechanical factors regarding anatomical barriers? Skin, Epithelium membrane, Desquamation, All of

the given

•  Lymph nodes, spleen and payer’s patches are. Secondary lymphoid

organs

•  Substance that is non-immunogenic but can react with products of specific immune response called..... Heptan
•  Humans can make 10⁷ to 10⁸ different Ab molecules
•  T-cells maturation in… Thymus
•  Ag & Ab reaction which can be detected on the basis of substrate utilization by enzyme …ELISA
•  Nature of Ag & Ab reactions... Non covalent bonding Immunology is the study of ....both immune system & immune response
•  Lag phase of secondary exposure is... Shorter as compare to primary

exposure

•  Peristalsis movement occurs in digestive tract
•  Valency is the Number of antigenic determinants which can bind with immunoglobulin.
•  Ag is presented to T-cells with..... Class II MHC
•  Suppose 10,000 lymphocytes recirculate every hour. If 100 of these encounter an antigen in lymph node then what percentage it achieved... 1%.
•  Antigen selects those clones of cells that have the appropriate receptor.
•  Suppose 10,000 lymphocytes recirculate every hour. If 100 of these encounter an antigen in the lymph node. What percentage is activated?

(1%)

•  Another term used for the physical barriers of innate immune system.....(Anatomical Barriers)
•  Which of the following are primary lymphoid organ.... (Bone Marrow,

Thymus)

•  Which secondary lymphoid organ is responsible for the filtration of blood..... (Spleen)
•  (Phagocytosis)....... The process of engulfing the invading or infectious agent by phagocytes.
•  A substance that is non-immunogenic but can react with products of specific immune response......(Hapten)
•  Which antibodies are complement fixing antibody......( IgM and IgG)
•  IgG exist in the form of......( Monomer)
•  Strength of binding of antigen with many antigenic determinant & multivalent antibody........(Avidity)
•  Agglutinate is term used for visible clumps formation in.......(Agglutination)
•  The process by which a B-Cell changes the class of Ab but not specificity..........(Class Switching)
•  Antibody from a single antibody producing B-cell.....(Monoclonal Ab)