ZOO501 Final Term Important Questions Spring 2025 by Muhammad Zaman
- Type
- Final term past paper
- Course
- ZOO501 Developmental Biology
- Size
- PDF 879 KB
- Updated
- 23 Oct 2026
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Protostomes
- The Ecdysozoa includes those animals that molt. Its major constituent is
- The second major group of protostomes are the Lophotrochozoa. They are characterized by a common type of cleavage (spiral), a common larval form, and a distinctive feeding apparatus.
These phyla include annelids, molluscs, and flatworms.
Deuterostomes
- From the Greek term meaning "mouth second."
- In this group, the anus forms first from the blastopore, followed by the mouth.
- Includes phyla like chordates (e.g., vertebrates) and echinoderms (e.g., starfish).
Three basic modes of commitment
The three basic modes of commitment in embryonic development are:
1. Autonomous Specification:
Cells acquire specific fates based on the differential distribution of cytoplasmic molecules in the egg.
- Characteristic of most invertebrates, leading to "mosaic" development where cells cannot change their fate if removed.
- In autonomous specification, certain cytoplasmic molecules present in the egg determine the fate of cells.
- This type of specification is common in most invertebrates.
- Cell type specification happens before any large-scale embryonic cell migration.
- This autonomous specification leads to a pattern of development called mosaic development. It’s like the embryo is made up of independent self-differentiating parts, just like a mosaic.
- Invariant cleavages occur, producing the same lineages in each embryo of the species.
- The fate of blastomeres are invariant.
- Produces “mosaic” (“determinative”) development: cells cannot change fate if a blastomere is lost.
2. Conditional Specification:
- Cells' fates depend on interactions with neighboring cells, making this mode regulative.
- Typical of vertebrates; cells can alter their fate if others are removed, allowing for compensation (e.g., identical twins).
- Conditional specification is a characteristic found in all vertebrates and a few invertebrates.
- o In this type of specification, cells interact with each other to determine their fate.
- o The relative positions of cells become important in this process.
- o Unlike in autonomous specification, the fate of cells is not predetermined and can vary.
- o Variable cleavages occur, meaning that cells do not have fixed assignments.
- Additionally, there are significant cell rearrangements and migrations that happen before or during specification.
- o Capacity for "regulative" development: allows cells to acquire different functions.
3. Syncytial Specification:
- Found in many insects, where interactions occur between different parts of a single multinucleate cell (syncytium).
- Insects like Drosophila use mRNA gradients (e.g., Bicoid and Nanos proteins) to specify body regions.
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